PLC 2050
With the capability to purify compounds by preparative HPLC and flash chromatography on the same instrument, Gilson's PLC 2050/2250/2500 Purification Systems simplify and streamline compound purification. These compact systems feature UV/VIS detection with an optional upgrade to a diode array detector (DAD) or evaporative light scattering detection (ELSD), an integrated pumping system, fraction collector, touchscreen control, and Gilson Glider Prep Software.
These customizable instruments are available in simple configurations for basic applications, but with a wide range of upgrade options to meet your lab's demands. PLC 2050 and PLC 2250 Purification Systems with Autosampler are configured with a VERITY® GX-241 Liquid Handler and VERITY 4020 Single Syringe Pump for automated sample injections for increased throughput. These systems allow you to queue samples and create multiple, unattended runs.
High Performance Features
• Intuitive touchscreen interface for easy method writing and modifying of parameters
• Built-in automatic injection valve
• Two or four independent solvent inlets for binary or quaternary gradients
• Three-rack fraction collector capacity with unlimited collection cycles
• Variable dynamic mixing chamber
• Dual reciprocating pump technology
• Four-wavelength UV/VIS or DAD detector
• Conductivity/pH monitor
• HPLC columns from 10 mm to 100 mm
PLC Purification System Models
PLC 2050: Flow rates up to 50 mL/min with pressure up to 300 bar
• Prep HPLC: 10-30 mm diameter ID columns
• Flash Chromatography: 2.5-70 g cartridges
PLC 2250: Flow rates up to 250 mL/min with pressure up to 230 bar
• Prep HPLC: 10-50 mm diameter ID columns
• Flash Chromatography: 10-600 g cartridges
PLC 2500: Flow rates up to 500 mL/min with pressure up to 110 bar
• Prep HPLC: 20-100 mm diameter ID columns
• Flash Chromatography: up to 1.2 kg cartridges
Specifications
| PLC 2050/2250/2500 Purification Systems | ||
| Flow Rate/Max Pressure | PLC 2050 | PLC 2250 | PLC 2500 |
| 50 mL/min, 300 bar (4 351 psi) | 250 mL/min, 230 bar (3 336 psi) | 500 mL/min, 110 bar (1 595 psi) | |
| Flow Rate Performance | 2% accuracy (with H2O degassed at 20°C) | ||
| Repeatability better than 0.5% | |||
| Linear response from 2 to 98 % | |||
| Binary Gradient (Standard) or Quaternary (Optional) Injection | Automatic or manual injection through sample loop with injection valve (optional) | ||
| Additional injection pump (optional) | |||
| GX-241 Liquid handler (optional) | |||
| Gradient | Binary Gradient (Standard) | ||
| Quaternary (Optional) | |||
| System Protection | Software with minimum and maximum pressures adjustable | ||
| Control | Via computer software “Gilson Glider Prep” | ||
| Storage | Up to 32 methods in software memory and 80 GB of hard disk memory | ||
| AC Mains Supply Voltage | 110V and 240 V ; 50/60 Hz (wattage: 350 W max.) | ||
| Electrical Protection | Delayed action fuses T 6.3A H 250 V | ||
| Power Distribution | TT or TN power system only, transient over-voltages according to installation category II, Class 1 equipment, requires mains socket plug with protective earth terminal | ||
| Switching Valve | Column Switching Valve,Automatic(Optional) | ||
| Column Switching Valve Manual(Optional) | |||
| Column Size with Optional Column Holder Kit |
Maximum height: 400 mm Maximum diameter: 115 mm |
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| Detector Options | Ultraviolet (UV) single wavelength detector, 254 nm filter | ||
| dual wavelength detector, 254 and 280 nm filters (optional) | |||
| UV detector 4-wavelength diode array detector (DAD) 200-400 nm (optional) | |||
| UV/VIS detector 4-wavelength DAD 200-600 nm (or 200-840 nm) (optional) | |||
| VERITY® 1900 MS detector (optional) | |||
| VERITY® 1810 Conductivity Monitor (optional) | |||
| PREPELS II Detector (optional) | |||
| Fraction Collector |
Several rack options available. Backflush valve (automatic) Column switching valve (automatic or manual) Fraction collector cover |
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Supporting Literature
| User's Guides | |
|---|---|
| PLC Purification System User's Guide | Download (EN) |
| Brochures | |
| Verity Brochure | Download (EN) |
| Purification Brochure | Download (EN) |
| Flyers | |
| PLC Purification With CPC Column | Download (EN) |
| Articles | |
| CPC Cost Effective Approach to Purification of Cannabinoids | Download (EN) |
| Technical Notes | |
| Introduction to Centrifugal Partition Chromatography | Download (EN) |
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